CASE REPORT
Treatment-related mortality in the course of acute lymphoblastic leukemia – case report
1
Student Scientific Society / Department of Paediatric Haematology, Oncology and Transplantology, Medical University, Lublin, Poland
These authors had equal contribution to this work
Corresponding author
Karol Bigosiński
Student Scientific Society / Department of Paediatric Haematology, Oncology and Transplantology, Medical University, 20-093 Lublin, Gębali 6, Poland
Student Scientific Society / Department of Paediatric Haematology, Oncology and Transplantology, Medical University, 20-093 Lublin, Gębali 6, Poland
KEYWORDS
TOPICS
ABSTRACT
The treatment of acute lymphoblastic leukemia (ALL) in children has become increasingly effective over the years. Currently, the cure rate is about 90%. This has become possible due to the use of combinations of appropriate chemotherapeutics in very high, often maximum doses. This is associated with the occurrence of so-called treatment-related mortality (TRM), the main cause of which is infections. The case report is presented of a 12-year-old patient who contracted a respiratory syncytial virus (RSV) infection during the consolidation phase of ALL treatment. The course of the infection was so severe that despite intensive antimicrobial treatment and a stay in an intensive care unit (ICU) the patient died. This indicates the absolute necessity of constant monitoring of a patient’s condition and consideration of early inclusion of antimicrobial prophylaxis, especially in patients at risk.
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