Meningococcal meningitis is an inflammation of the meninges caused by Neisseria meningitidis. Clinically, meningococcal meningitis does not differ from other bacterial meningitis. Initially, the symptoms of the disease may be non-specific, such as fever, muscle pain, and weakness, only later do the symptoms typical of meningitis appear. Adolescents and adults have a lower incidence of neck stiffness and altered consciousness than younger patients. The disease is characterized by a rapid onset and progression of symptoms within a few hours. The detection of Neisseria meningitidis in the cerebrospinal fluid allows for the correct diagnosis and appropriate treatment. Antibiotics reduce mortality in meningococcal disease by up to five times. The case is presented of a young adult patient with a history of viral meningitis in childhood who was hospitalized for severe meningococcal meningitis and successfully treated.
Wang B, Santoreneos R, Giles L, et al. Case fatality rates of invasive meningococcal disease by serogroup and age: A systematic review and meta-analysis. Vaccine. 2019;37(21):2768–2782. https://doi.org/10.1016/j.vacc....
Chaudhuri A, Martinez-Martin P, Kennedy PG, et al. EFNS Task Force. EFNS guideline on the management of community-acquired bacterial meningitis: report of an EFNS Task Force on acute bacterial meningitis in older children and adults. Eur J Neurol. 2008;15(7):649–59. https://doi.org/10.1111/j.1468....
Dwilow R, Fanella S. Invasive meningococcal disease in the 21st century-an update for the clinician. Curr Neurol Neurosci Rep. 2015;15(3):2. https://doi.org/10.1007/s11910....
Mrozowska-Nyckowska K, Zbrzeźniak J, Paradowska-Stankiewicz I. Meningitis and encephalitis in Poland in 2020. Przegl Epidemiol. 2022; 76(3):371–384. https://doi.org/10.32394/pe.76....
Mörs K, Braun O, Wagner N, et. al. Influence of gender on systemic IL-6 levels, complication rates and outcome after major trauma. Immunobiology. 2016;221(8):904–10. doi:10.1016/j.imbio.2016.03.005.
Caugant DA, Brynildsrud OB. Neisseria meningitidis: using genomics to understand diversity, evolution and pathogenesis. Nat Rev Microbiol. 2020;18(2):84–96. https://doi.org/10.1038/s41579....
Cabellos C, Pelegri´n I, Benavent E, et al. Invasive meningococcal disease: impact of short course therapy. A DOOR/RADAR study. J Infect. 2017;75:420–425.
Tolaj I, Dreshaj S, Qehaja E, et al. Dexamethasone as adjuvant therapy in the treatment of invasive meningococcal diseases. Med Arh. 2010; 64(4):228–30.
The Journal of Pre-Clinical and Clinical Research welcomes article submissions and does not charge a publication fee. Submit your article today and gain worldwide visibility for your article.
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.