CASE REPORT
Complex neuropsychiatric disorders following Listeria monocytogenes encephalitis and meningitis in a 16-year-old
immunocompromised patient
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1
Student Research Group, Department of Paediatric Neurology, Medical University, Lublin, Poland
2
Department of General Surgery, 1st Military Clinical Hospital with the Outpatient Clinic, Lublin, Poland
3
Department of Neonatology, Pathology and Neonatal Intensive Care, Stefan Cardinal Wyszyński District Specialist Hospital, Lublin, Poland
4
Department of Paediatric Neurology, Medical University, Lublin, Poland
Corresponding author
Natalia Biedroń
The Student Research Group,
Department of Paediatric Neurology, Medical University, Lublin,
Poland
KEYWORDS
TOPICS
ABSTRACT
Introduction:
Listeriosis in immunocompetent patients usually presents as gastroenteritis with fever; however, it can
occasionally lead to severe infections such as meningitis and sepsis. The case report concerns a boy with several autoimmune diseases on immunosuppressive therapy, who developed behavioural issues due to Listeria monocytogenes (LM) infection.
Case Report:
The patient was suspected of meningitis, and polymerase chain reaction testing of the cerebrospinal fluid
revealed the presence of LM. The patient’s condition worsened, neurological symptoms increased, and the patient developed sepsis, requiring treatment in the Intensive Care Unit (ICU). After a monthly stay in the ICU, contact with the patient returned, but the infection caused severe behavioural changes. Autoimmune encephalitis was suspected and psychiatric treatment initiated.
Conclusions:
This case illustrates the broader issue of LM infection and emphasizes the need for special attention in the
care of immunocompromised patients.
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