Introduction and objective:
Epilepsy has a significant impact on patients’ psychiatric condition. Epidemiological studies have shown that comorbid psychiatric disorders can occur in about 20–40% of patients with epilepsy. The aim of th study is to raise awareness of how much neuropsychiatric comorbidity exists, and to expand knowledge about this problem.

Review methods:
The review was based on articles from the PubMed and Google Scholar databases, by searching terms: epilepsy; epilepsy comorbidity; epileptic syndromes, seizures, mental disorders, depression, suicide, neuro-developmental disorders, suicide attempt, self-injurious behaviour, quality of life.

Brief description of the state of knowledge:
Numerous studies conducted over the past years show an increase in the prevalence of mental disorders occurring in patients with epilepsy, compared to healthy people. Mental disorders can be part of an epileptic seizure, have a temporal relationship with them, or occur independently. Problems in the adult population mainly involve depression and anxiety. Along with epilepsy, psychotic and personality disorders can co-occur. In the paediatric population, one of the most common problems reported by parents is attention deficit disorder, especially with ADHD. Furthermore, anxiety disorders and depression are at the forefront in adolescents. The correlation with suicide in epilepsy patients, both adults and minors, is significant, as suicide risk is up to 10 times higher, compared to the general population.

Summary:
Comorbidity of mental disorders in the course of epilepsy poses significant difficulties for both patients and clinicians. Thus, in the proper manage of those patients, it is important to possess a comprehensive knowledge about the prevalence of such phenomenon, as well as about the different complications and risks associated with it, including the possibility of suicide.