Introduction and objective:
Dravet syndrome (DS) is a condition associated with a genetic mutation that causes epileptic seizures resistant to classical treatment. Symptoms may also co-occur that overlap with features of the neurodevelopmental disorder Autism Spectrum Disorder (ASD). The aim of the study is to demonstrate the relationship between the occurrence of Dravet syndrome and autism, and to provide suggestions relating to the cause of the co-occurrence of these disorders.

Review methods:
An evaluation was conducted of the literature available in the PubMed and Scopus databases Articles published between 2018 –2024 were searched using the phrases ‘epilepsy’, ‘autism spectrum disorder’, ‘autism’, ‘pathogenesis’, ‘case’, ‘Dravet syndrome’, ‘child’, ‘prevalence’, ‘epidemiology’, ‘therapy’, ‘treatment’, ‘symptoms’, ‘causes’, and ‘genetics’.

Brief description of the state of knowledge:
Epilepsy is a neurological disorder characterized by recurrent seizures and is correlated with ASD. The relationship between these disorders is incompletely understood. Similarly, it has been shown that Dravet syndrome can have symptoms that overlap with or even co-occur with features of autism. There are several hypotheses explaining this finding. A de novo mutation in the SCN1A gene is most often responsible for the onset of DS, which could indicate behavioural disorders and autistic behaviour, among other problems associated with this disease entity.

Summary:
Dravet syndrome not infrequently manifests with complaints that may resemble ASD. There are a number of assumptions that explain the reason for the correlation between DS and ASD, based primarily on the pathophysiology of Dravet syndrome.