CASE REPORT
Connecting the dots – rapid diagnostic process for eosinophilic granulomatosis with polyangiitis in a patient with hemoptysis
 
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1
Chair and Department of Pneumonology, Oncology and Allergology, Medical University, Lublin, Poland
2
Student Research Association of Pulmonology, Chair and Department of Pneumonology, Oncology and Allergology, Medical University, Lublin, Poland
3
Chair of Internal Medicine and Department of Internal Medicine in Nursing, Medical University, Lublin, Poland
CORRESPONDING AUTHOR
Anna Grzywa-Celińska   

Chair and Department of Pneumonology, Oncology and Allergology, Medical University , Lublin., ul. Jaczewskiego 8, 20-954, Lublin, Poland
 
 
KEYWORDS
TOPICS
ABSTRACT
Introduction:
Eosinophilic granulomatosis with polyangiitis (eGPA) is a rare type of vasculitis. We described the case of the patient who was admitted to our Department due to haemoptysis, in whom the model-based clinical reasoning and quick diagnostic process led to the diagnosis and referral of the patient to specialists dealing with the treatment of this disease. We wanted to emphasize the fact that the patient developed symptoms of the disease many years before diagnosis. However, these clinical problems were treated individually. A broader reflection of the patient’s symptoms may have led to earlier diagnosis and implementation of adequate treatment

Objective:
The aim of the study is to underline the importance of clinical reasoning on the example of eGPA model diagnostics. The combination of several clinical findings led to the correct diagnosis, which enabled the patient to obtain treatment and improved further prognosis.

 
REFERENCES (15)
1.
Groh M, Pagnoux C, Baldini C, et al. Eosinophilic granulomatosis with polyangiitis (Churg-Strauss) (EGPA) Consensus Task Force recommendations for evaluation and management. Eur J Intern Med. 2015; 26(7): 545–53. https://doi.org/10.1016/j.ejim....
 
2.
Chakraborty RK, Aeddula NR. Churg Strauss Syndrome. https://www.ncbi.nlm.nih.gov/b... (access: 2022.01.04).
 
3.
Comarmond C, Pagnoux C, Khellaf M, et al. Eosinophilic granulomatosis with polyangiitis (Churg-Strauss): clinical characteristics and long-term follow up of the 383 patients enrolled in the French Vasculitis Study Group cohort. Arthritis Rheum. 2013; 65(1): 270–81. https://doi.org/10.1002/art.37....
 
4.
Almaani S, Fussner LA, Brodsky S, et al. ANCA-Associated Vasculitis: An Update. J Clin Med. 2021; 10(7): 1446. https://doi.org/10.3390/jcm100....
 
5.
Furuta S, Iwamoto T, Nakajima H. Update on eosinophilic granulomatosis with polyangiitis. Allergol Int. 2019; 68(4): 430–436. https://doi.org/10.1016/j.alit....
 
6.
Saku A, Furuta S, Hiraguri M, et al. Longterm Outcomes of 188 Japanese Patients with Eosinophilic Granulomatosis with Polyangiitis. J Rheumatol. 2018; 45(8): 1159–1166. https://doi.org/10.3899/jrheum....
 
7.
Durel CA, Berthiller J, Caboni S, et al. Long-Term Followup of a Multicenter Cohort of 101 Patients With Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss). Arthritis Care Res (Hoboken). 2016; 68(3): 374–87. https://doi.org/10.1002/acr.22....
 
8.
Moosig F, Bremer JP, Hellmich B, et al. A vasculitis centre based management strategy leads to improved outcome in eosinophilic granulomatosis and polyangiitis (Churg-Strauss, EGPA): monocentric experiences in 150 patients. Ann Rheum Dis. 2013; 72(6): 1011–1017. https://doi.org/10.1136/annrhe....
 
9.
Tsurikisawa N, Oshikata C, Kinoshita A, et al. Longterm Prognosis of 121 Patients with Eosinophilic Granulomatosis with Polyangiitis in Japan. J Rheumatol. 2017; 44(8): 1206–1215. https://doi.org/10.3899/jrheum....
 
10.
Wiatr E, Gawryluk D. Primary systemic ANCA-associated vasculitis — recommendations concerning diagnosis and treatment. Pneumonol. Alergol. Pol. 2013; 81: 479–491.
 
11.
Settipane RA, Peters AT, Chiu AG. Chapter 6: Nasal polyps. Am J Rhinol Allergy. 2013; 27: S20–5. https://doi.org/10.2500/ajra.2....
 
12.
Madej M. Ocena aktywności zapalenia naczyń. Przegl Reumat. 2008; 3–4: 9.
 
13.
Chen Y, Guo X, Zhou J, et al. Cardiac Involvement in Eosinophilic Granulomatosis With Polyangiitis: A Retrospective Study in the Chinese Population. Front Med (Lausanne). 2020; 7: 583944. https://doi.org/10.3389/fmed.2....
 
14.
André R, Cottin V, Saraux JL, et al. Central nervous system involvement in eosinophilic granulomatosis with polyangiitis (Churg-Strauss): Report of 26 patients and review of the literature. Autoimmun Rev. 2017; 16(9): 963–969. https://doi.org/10.1016/j.autr....
 
15.
Bettiol A, Urban ML, Dagna L, et al. European EGPA Study Group. Mepolizumab for Eosinophilic Granulomatosis With Polyangiitis: A European Multicenter Observational Study. Arthritis Rheumatol. 2022; 74(2): 295–306. https://doi.org/10.1002/art.41....
 
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