CASE REPORT
The use of laser therapy in the treatment of recurrent herpes – report of two clinical cases
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1
Department of Oral and Periodontal Diseases, Medical University, Łódź, Poland
2
Department of Maxillofacial Surgery, Medical University, Łódź, Poland
3
Department of Oral Pathology, Medical University, Łódź, Poland
These authors had equal contribution to this work
J Pre Clin Clin Res. 2026;20(1):11-15
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ABSTRACT
The article discusses current therapeutic approaches to recurrent herpes and presents two clinical cases of lesions managed
with laser-based therapy. HSV-1 and HSV-2 are among the most common human pathogens, responsible for oral and
genital infections. Standard treatment with acyclovir (ACV) inhibits viral replication and relieves symptoms, but does not
eliminate latent infection and therefore does not prevent recurrences. Increasing antiviral resistance highlights the need for
complementary treatment options. Photodynamic therapy (PDT), including antimicrobial photodynamic therapy (aPDT) and
photobiomodulation (PBM), offer non-invasive approaches that may reduce inflammation, promote healing, and improve
patient comfort. In the presented cases, recurrent herpes lesions were treated using a 635 nm diode laser, resulting in rapid
symptom relief, accelerated healing, and no recurrence during follow-up.
Bielecka-Kowalska NP, Bielecki-Kowalski BM, Kłosek S. The use of laser therapy in the treatment of recurrent herpes – report of two clinical
cases. J Pre-Clin Clin Res. 2026;20(1):11–15. doi:10.26444/jpccr/218261
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