RESEARCH PAPER
Comparative study of cutaneous manifestations in patients with chronic kidney disease , patients on haemodialysis, and renal transplant recipients
 
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Care Institute of Medical Sciences
CORRESPONDING AUTHOR
rajitha muntha   

care institute of medical sciences, care hospital road no 10, banjara hills, 500034 hyderabad, India
 
J Pre Clin Clin Res. 2018;12(1):11–15
KEYWORDS
TOPICS
ABSTRACT
Introduction:
A wide variety of skin diseases occur in patients with chronic renal failure (CRF). These diseases are either related to the underlying chronic kidney disease (CKD) or to its treatment modalities like hemodialysis (HD) and renal transplant (RT). The studies comparing cutaneous manifestations in CKD, CKD with HD and RT recipients (RTR’s) have been limited.

Material and methods:
106 patients with CKD, 101 patients with CKD and who are undergoing HD and 80 RTR’s having at least one dermatological complaint formed the study groups. Detailed cutaneous examination was done for all patients and dermatological manifestations were compared among various study groups.

Results:
The most prevalent finding in CKD patients was xerosis (69%) followed by pruritus (67%) and pigmentation disorders (11%). Other cutaneous manifestations included acquired perforating diseases(APD) (7.5%); fungal (9.4%), viral (7%) and bacterial (2%) infections and nail changes(11%).The manifestations found in CKD patients on HD were xerosis (65%) followed by pruritus (62%),pigmentation disorders (20%), APD (6%); fungal (9.9%), viral (4%) and bacterial (5%) infections and nail changes(19%). In RTR’s, however, infections (47%) were the most prevalent finding. Others were xerosis(20%), pruritis(9%),pigmentation disorders(5%),APD (1%),nail changes(5%) and lesions of aesthetic interest(14%). Manifestations like pruritus, xerosis, hyperpigmentation and infections differed significantly when compared amongst three groups.

Conclusions:
Cutaneous manifestations are common and different in CKD, HD and RTR group of patients. While xerosis and pruritus were common in CKD and HD group, infections were most prevalent in RTRs.

 
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