RESEARCH PAPER
The weaning-related changes in amino acids status of blood plasma in piglets
1
Department of Comparative Anatomy and Anthropology, Maria Curie-Skłodowska University, Lublin, Poland
2
Department of Biochemistry and Animal Physiology, Faculty of Veterinary Medicine, University of Life Sciences, Lublin, Poland
Corresponding author
Piotr Dobrowolski
Department of Comparative Anatomy and Anthropology, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, Poland.
Department of Comparative Anatomy and Anthropology, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, Poland.
J Pre Clin Clin Res. 2008;2(1):71-74
KEYWORDS
ABSTRACT
The aim of this study was to investigate changes of hormones and plasma amino acids in piglets subjected to weaning procedure. Twelve male piglets (Large Polish White breed) were used in the experiment. Piglets were held with their mothers from birth up to the 30th day of neonatal life, and on that day weaned, and housed individually for 5 days. Selected plasma amino acids and insulin-like growth factor-1 (IGF-1), growth hormone (GH) and cortisol concentrations in blood serum of piglets before and after weaning were analyzed. IGF-1 concentration showed a tendency to decrease in 35-day-old animals. There was no change in the values of cortisol and GH concentration between not-weaned and weaned piglets. Cysteic acid plasma concentration was signifi cantly higher in piglets after weaning, but the levels of taurine, threonine, glutamine, alanine, valine, leucine, ornithine were lower in 35-day-old piglets. In piglets after weaning there was the tendency to an increase in plasma
concentration of arginine, glutamate and glycine. Analysis of plasma concentrations of other amino acids showed a tendency to lower values in piglets at the age of 35 days of postnatal live. The mechanisms of the homeostatic control of amino acids metabolism in blood plasma were not able to sustain an adequate range of their concentrations after weaning. The obtained results of lowered levels of the majority of amino acids indicate that inhibited growth rate and body weight gain of weaned piglets might be the cause of the observed eff ects.
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