Heterotopic neuroglial tissue in lumbar spinal canal – Case report
More details
Hide details
Department of Neurosurgery and Paediatric Neurosurgery, Medical University, Lublin, Poland
Neuropathological Laboratory, Department of Neurosurgery and Pediatric Neurosurgery, Medical University of Lublin, Poland;
Corresponding author
Bartłomiej Kulesza   

Department of Neurosurgery and Paediatric Neurosurgery, Medical University,Strumykowa 96, 20-855 Lublin, Poland
J Pre Clin Clin Res. 2018;12(4):117-119
Ectopic and heterotopic both refer to cells displaced from their normal site – ectopic cells occur outside their organ of origin whereas heterotopic cells are in an aberrant location within their organ of origin. The most common localization of heterotopic neuroglial tissue (HNT) is the nasal region. We report a case of 69-years-old man who presented with long history of lumbosacral pain with paresis of the inferior limb. MRI examination detected a cystic tumour located at the L1-L2 level. Histologic examination revealed the presence of heterotopic neuroglial tissue, containing synaptophysin, glial cells and encircled meninges.
Sarnat HB: Ectopic or heterotopic? An appeal for semantic precision in describing developmental disorders of the nervous system. Pediatr Neurol.1995;13:178–179.
Ducic Y: Nasal gliomas. J Otolaryngol.1999; 28: 285–287.
Hendrickson M, Faye-Petersen O, Johnson DG: Cystic and solid heterotopic brain in the face and neck: a review and report of an unusual case. J Pediatr Surg.1990; 25:766–768.
Behar PM, Muller S, Gerber ME, Todd NM: Heterotopic neuroglial tissue causing airway obstruction in the new born. Arch Otolaryngol Head Neck Surg. 2001; 127: 997–1002.
Wolbach SB: Congenital rhabdomyoma of the heart. Report of a case associated with multiple nests of neuroglia tissue in the meninges of the spinal cord. J Med Res.1907;16;495–520.
Penner CR, DDS, Thompson LRD. Nasal Glial. Heterotopia: A Clinicopathologic and Immuno phenotypic Analysis of 10 Cases With a Review of the Literature. Annals of Diagnostic Pathology. 2003;7(6):354–359.
Conner AK, Fung KM, Peterson JE, Glenn CA, Martin MD: Ectopic ganglion in cauda equina: case report. J Neurosurg Spine 2016; 12: 1–4.
Shrestha BB, Ghimire P, Ghartimagar D, Jwarchan B, Lalchan S, Karmacharya M: Mature brain tissue in the sacrococcygeal region. Surg Case Rep. 2016;5: 1–3.
Journals System - logo
Scroll to top