CASE REPORT
Diffuse large B cell lymphoma of the oral cavity – Case report
| 1 | Department of Maxillofacial Surgery, Medical University, Lublin, Poland; Haematooncology Department, Medical University, Lublin, Poland |
CORRESPONDING AUTHOR
Anna Gawęda
Department of Maxillofacial Surgery, Medical University, Staszica 11, 20-081 Lublin, Poland
Department of Maxillofacial Surgery, Medical University, Staszica 11, 20-081 Lublin, Poland
J Pre Clin Clin Res. 2014;8(1):27–29
KEYWORDS
ABSTRACT
The study presents an atypical location of Non-Hodgkin lymphoma of the oral cavity in the area of the palate. Pathological changes of the mucosa of the palate in an 85-year-old female patient had been developing for many years as a result of upper denture irritation without any major symptoms. Histological examination revealed a Diffuse large B cell lymphoma. Due to being advanced in years, the patient was qualified for the local radiotherapy. In this particular case, the clinical picture of lymphoma imitated an inflammation of the mucosa of the oral cavity which resulted in delayed diagnosis and treatment.
REFERENCES (16)
1.
Landis S, Murray T, Bolden S. Canser Statistics 1999. Canser J. Clin. 1999, 49, 28–31.
2.
Lewandowski L, Nowaczyk MT. Non-Hodgkin’s Lymphomas oral Cavity and Neck-diagnosis, treatment. Poznańska Stom. 2002, 24, 15–18.
3.
Frei M, Dubach P, Reichart PA, Schmitt AM, Muller-Garamvolgyi E, Bornstein MM. diffuse swelling of the buccal mucosa and palate as first and only manifestation of an extranodal non-Hodgkin, double-hit, lymphoma; report of a case. Oral Maxillofac. Surg, 2012, 16, 69–74.
4.
Chloupek A, Sarosiek T, et al. Malignant B-cell lymphoma. A case report
of a malignant lymphoma of high grade malignancy located in the oral
cavity. Cas. Stomat. 2003; 56, 12, 857–864.
5.
Nadendla KL, Meduri V, Paramkusam G. Imaging characteristics of diffuse large cell extranodal non-Hodgkin’s lymphoma involving the palate and maxillary sinus: a case report. Imaging Science in Dentistry. 2012, 42, 111–114.
6.
Epstein JB, Epstein JD, Le ND, Gorsky M. Characteristics of oral and paraoral malignant lymphoma: a population -based review of 361 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endos.2001;92:519–525.
7.
Jaffe ES et al.(2001) In Kleihues, P.Sobin, L.(eds) WHO classification of Tumours.ARC Press, Lyon.
8.
Gerber-Leszczyszyn H, Łuczak k, Ćwioro F. Head and Neck non Hodgkin lymphoma. Czas stom.1993, 46: 115–118.
9.
Etemad-Moghadam’s, Tirgary F, Kehavarz S, Alaeddini M. Head and neck non-Hodgkin’s lymphoma: a 20-year demographic study of 381 cases. Int. J. Oral Maillofac. Surg 2010, 39, 869–872.
10.
Sugimoto KJ et al.Primary gingival diffuse large B-cell lymphoma: a case report and a review of the literature. Int J Clin Exp Pathol.2014; 7(1): 418–424.
11.
Rosenwald A et al.The use of molecular profilling to predict survival after chemotherapy for diffuse large B-cell lymphoma. N Engl J Med. 2002.346: 1937–1947.
12.
Sato Y, Onishi N, Morito T, Takata K, Mizobuchi K, Nagatsuka H, Ichimura K, Tanaka T, Tamura M, Yoshino T.Patients with localized primary non-tonsillar oral diffuse large B-cell lymphoma exhibit favorable prognosis despite a non-germinal center B-cell –like phenotype.Cancer Sci.2009; 100: 42–46.
13.
Bhattacharyya I, Chehal HK, Cohen DM, et al. Primary diffuse large B-cell lymphoma of the oral cavity: germinal center classification. Head and Neck Pathol. 2010; 4, 181–191.
14.
Chung-Che Chang, Rowe JJ, Hawkins P. Mantle cell lymphoma of the hard palate: A case report and review of the differential diagnosis based on the histomorphology and immunophenotyping pattern. Med. Oral Pathol. Oral Radiol. Endod. 2003, 96, 316–320.
15.
Janas A, Grzesiak-Janas G. Non–Hodgkin extranodular lymphona of the palate. Pol.Merc.Lek.2006, 20, 120, 705–707.
16.
Guggisberg K, Jordan RCK. Mantle cell lymphoma of the oral cavity: case series and comprehensive review of the literature. Oral Surg. Oral. Path. Oral Rad. and Endodont. 2010, 109, 1, 98–104.
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.