Common variable immunodeficiency in an 11-year-old girl – a case report
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Department of Paediatrics and Allergy, Medical University, Lodz, Copernicus Memorial Hospital, Korczak Paediatric Centre, Lodz, Poland
Corresponding author
Joanna Pawłowska   

Department of Pediatrics and Allergy, Medical University of Lodz, Copernicus Memorial Hospital, Korczak Pediatric Centre, Lodz., Piłsudskiego 71, 90-329, Lodz, Poland
J Pre Clin Clin Res. 2020;14(1):14-17
Common variable immunodeficiency (CVID) is one of the most prevalent, heterogenous primary immunodeficiency syndromes in children and adults. Besides impaired immunoglobulin production by B cells, abnormalities in almost all components of the immune system have been desribed in CVID. The clinical pictures of CVID includes acute and chronic infections, inflammatory and autoimmune diseases, and can be associated with an increased incidence of cancer and lymphoma. Due to the plurality of clinical manifestations and different ages of occurance, diagnosis of CVID is difficult and belated in relation to primary symptoms. Patients with CVID require an integrated interprofessional team approach to minimalize complications of the disease and to improve patient outcomes. The article presents the clinical case of 11-yearold girl diagnosed with CVID in day-to-day medical practice.
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