RESEARCH PAPER
Epidemiology of non-invasive Aspergillosis of the maxillary sinuses – Clinical data from the Maxillofacial Surgery Clinic of the Medical University in Lublin, Poland, 2005–2014
 
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Chair and Clinic of Maxillofacial Surgery, Medical University of Lublin, Poland
CORRESPONDING AUTHOR
Jolanta Wojciechowicz   

Chair and Clinic of Maxillofacial Surgery, Medical University of Lublin, Staszica 11, 20-081 Lublin, Poland
 
J Pre Clin Clin Res. 2014;8(2):95–99
KEYWORDS
ABSTRACT
Fungi are organisms which occur in the human environment. One of the potential pathogenic fungi is Aspergillus which belongs to mould, and is an etiological factor of non-invasive fungal paranasal sinusitis. Objective. Epidemiological analysis of aspergillosis of the maxillary sinuses. Material and methods. Retrospective analysis of the medical histories of 41 patients treated in the Maxillofacial Surgery Department of Medical University in Lublin, Poland between 2005–2014 due to non-invasive aspergillus maxillary sinusitis. The patients’ gender, age, and etiopathogenesis of the condition with signs and symptoms, and methods of treatment were analysed. Histological examination was crucial in the final diagnosis. Results. The majority of the patients constituted women aged 29–72. The most common complaints were suborbital pain, rhinorrhoea and impaired nasal ventilation. All the patients were treated surgically, and pharmacologically with Fluconazole. Conclusion. Fungal maxillary sinusitis should be taken into account in every case of chronic maxillary sinusitis resistant to standard treatment. Women are more susceptible to Aspergillosis, and the risk factors for the disease are endodontic treatment of the maxillary teeth and fistula antro-oralis post extractionem. Surgical treatment sometimes should be complemented by pharmacological antimycotic treatment.
 
REFERENCES (23)
1.
Costa F, Polini F, Zerman N, Robiony M, Toro C, Politi M. Surgical treatment of aspergillus mycetomas of the maxillary sinus: review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol andEndod. 2007; 103: 23–29.
 
2.
Rudzki E. Alergeny. Odcinek 71 Aspergillus (narażenie niezawodowe). Med. Prakt. 2001; 11: 186–187 (in Polish).
 
3.
Klempous J, Pośpiech L, Rak J. Fungal rhinosinusitis. Medical mycology. 2000; 7: 99–105.
 
4.
Krzeski A, Donald C, Lanza C. Grzybica zatok przynosowych. In: Krzeski A, Janczewski G. Choroby nosa i zatok przynosowych. Warszawa, Sanmedia, 1997.p 229–237 (in Polish).
 
5.
deShazo RD, O’Brien M, Chapin K, Soto-Aguilar M, Swain R, Lyons M et al. Criteria for the diagnosis of sinus mycetoma. J Allergy Clin Immunol Pract. 1997; 99, 4: 475–485.
 
6.
Ferreiro JA, Carlson BA, Cody DT. Paranasal sinus fungus balls. Head Neck. 1997; 19, 6: 481–486.
 
7.
Eloy Ph, Grenier J, Pirlet A, Poirrier AL, Stephens JS, Rombaux Ph. Sphenoid sinus fungall ball: a retrospective study over a 10-year period. Rhinology. 2013; 51–2: 181–188.
 
8.
Krennmair G, Lenglinger F, Muller– Schelken H. Computed tomography in the diagnosis of sinus aspergillosis. J Craniomaxillofac Surg. 1994; 22, 2: 120–125.
 
9.
Martins WD, Ribeiro Rosa EA. Aspergillosis of the maxillary sinus: review and case report. Scand J Infect Dis. 2004; 36: 758–761.
 
10.
Beck-Mannagetta J, Necek D. Radiologic findings in aspergillosis of the maxillary sinus. Oral Surg Oral Med Oral Pathol Oral Radiol and Endod. 1986; 62: 345–349.
 
11.
Burnham R, Bridle C. Aspergillosis of the maxillary sinus secondary to a foreign body (amalgam) in the maxillary antrum. J Oral Maxillofac Surg Med Pathol. 2009;47:313–315.
 
12.
Odell E, Pertl C. Zinc as growth factor for Aspergillus sp. and the antifungal effects of root canal sealants. Oral Surg Oral Med Oral Pathol Oral Radiol and Endod. 1995; 79, 1: 82–87.
 
13.
Giardino L, Pontieri F, Savoldi E, Tallarigo F. Aspergillus mycetoma of the maxillary sinus secondary to overfilling of a root canal. J Endod. 2006; 32, 7: 692–694.
 
14.
Chobillon MAJ, Jankowski R. What are the advantages of the endoscopic canine fossa approach in treating maxillary sinus aspergillomas? Rhinology, 2004; 42, 4: 230–235.
 
15.
Lai JC, Lee HS, Chen MK, Tsai YL. Patient satisfaction and treatment outcome of fungus ball rhinosinusitis treated by functional endoscopic sinus surgery. Eur Arch Otorhinolaryngol.2011; 268, 2: 227–230.
 
16.
Nomura K, Asaka D, Nakayama T, Okushi T, Matsuwaki Y, Yoshimura T, et al. Sinus Fungus Ball in the Japanese Population: Clinical and Imaging Characteristics of 104 Cases. Int J Otolaryngol. 2013; Article ID 731640, 4 pages, http://dx.doi.org/10.1155/2013... (access: 2014.03.25).
 
17.
Dufour X, Kauffmann-Lacroix C, Ferrie JC, Goujon JM, Rodier MH, Karkas A et al. Paranasal sinus fungus ball and surgery: a review of 175 cases. Rhinology. 2005; 1: 34–39.
 
18.
Park GY, Kim HY, Min JY, Dhong HJ, Chung SK. Endodontic treatment: a significant risk factor for the development of maxillary fungal ball. Clin Exp Otorhinolaryngol. 2010; 3: 136–140.
 
19.
Nicolai P, Lombardi D, Tomenzoli D, Villaret AB, Piccioni M, Mensi M et al. Fungus ball of the paranasal sinuses: experience in 160 patients treated with endoscopic surgery. Laryngoscope. 2009; 119: 2275–2279.
 
20.
Nakaya K, Oshima T, Kudo T. New treatment for invasive fungal sinusitis: three cases of chronic invasive fungal sinusitis treated with surgery and voriconazole. Auris Nasus Larynx. 2010; 37, 2: 244–249.
 
21.
Tomczak H. Fungal infection in laryngology – problem of diagnosis and treatment. Advances in head and neck surgery. 2008; 2: 51–57.
 
22.
Stankiewicz C, Misiołek M. Miejsce operacji Caldwella-Luca we współczesnej rynologii [Place of Caldwell-Luc surgery in contemporary rhinology]. Magazyn Otolaryngologiczny. 2006; 5, 4: 107–110 (in Polish).
 
23.
Minutha R, Sriram N. A study of Caldwell-Luc approach in various etiologies. Journal of Evolution of Medical and Dental Sciences. 2013; 2(36): 7015–7023.
 
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