RESEARCH PAPER
Ultrastructural haemomicrocircular channel links of rat testicle in streptozotocin-induced diabetes
| 1 | Danylo Galytskiy National Medical University, L’viv, Ukraine |
| 2 | Department of Animal Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Sciences, Lublin, Poland |
| 3 | Department of Human Anatomy, Faculty of Medicine, University of Lublin, Poland |
CORRESPONDING AUTHOR
Agata Wawrzyniak
Department of Animal Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Poland
Department of Animal Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Poland
J Pre Clin Clin Res. 2014;8(2):86–89
KEYWORDS
ABSTRACT
The first changes in rat testicle haemomicrocircular channel links ultrastructural arrangement are noticed already in a 2-week run of streptozotocin-induced diabetes mellitus, and accumulate throughout next periods of the experiment. Angiopathy is a trigger mechanism for diabetic development of testicle structural changes. This finding is a basis for further morphologist and clinicist surveys for the purpose of new diabetic testicle pathology diagnostics, prevention, and elaboration of treatment techniques.
REFERENCES (18)
1.
Borovkova SA. Questions of pathogenesis of diabetic angiopathy. Bukovina Medical Bulletin. 2006; 2: 132–135.
2.
Моgylnytska LA. Endothelial dysfunction in diabetes mellitus type 2. Endocrinology. 2001; 1: 95–103.
4.
Arikawe AP, Oyerinde A, Olatunji Bello II, Obika LFO. Streptozotocin diabetes and insulin resistance impairment of spermatogenesis in adult rat testis: central Vs local mechanism. Niger J Physiol Sci. 2012; 27(2): 171–179.
5.
Gamal MA. Hassan and Tarek Abdel M. Structural Changes in the Testes of Streptozotocin-Induced Diabetic Rats. Suez Canal Univ Med J. 2001; 4: 17–25.
6.
Ji-Ping Liu, Liang Feng, Ming-hua Zhang, Dong-ying Ma, Shu-yuan Wang, Junfei Gu, Qiang Fu, Rong Qu, Shi-ping Ma. Neuroprotective effect of Liuwei Dihuang decoction on cognition deficits of diabetic encephalopathy in streptozotocin-induced diabetic rat. J Ethnopharmacol. 2013; 150: 371–381.
7.
Flyvbjerg A. Diabetic angiopathy, the complement system and the tumor necrosis factor superfamily. Nat Rev Endocrinol. 2010; 6: 94–101.
8.
Hammes HP. Pathophysiological mechanisms of diabetic angiopathy. J Diabetes Complications. 2003; 17(2): 16–19.
9.
Škrha J. Pathogenesis of angiopathy in diabetes. Acta Diabetol. 2003; 40(2): 324–329.
10.
Fereshteh K, Ozra N, Shahriar A, Vahid N. Sesame effects on testicular damage in streptozotocin-induced diabetes rats. A J Phytomed. 2013; 3: 347–355.
11.
Roghani M, Baluchnejadmojarad T, Roghani Dehkordi F. The Sesame Lignan Sesamin Attenuates Vascular Permeability in Rats with Streptozotocin-Induced Diabetes: Involvement of Oxidative Stress. Int J Endocrinol Metab. 2011; 9: 248–252.
12.
Setchell BP. Human reproduction. The missing parts of the puzzle. Adv Exp Med Biol. 1997; 424: 1–15.
13.
Fukudome D, Matsuda M, Kawasaki T, Ago Y, Matsuda T. The radical scavenger edaravone counteracts diabetes in multiple low-dose streptozotocin-treated mice. Eur J Pharmacol. 2008; 1:164–169.
14.
Pshenychnyy NF. Model microcirculator in the testes in normal and varicocele. J Morphol. 2005; 11: 60–62.
15.
Лучицкий EV. Structural-functional state and the blood supply to the testes in diabetic patients. Bukovina medical Bulletin. 2002; 1: 79–81.
16.
Ivasyuk IJ. Changes in the blood vessels and testicular parenchyma after his injury. Uzhhorod University Scientific Herald, Series Medicine 2004; 23: 18–19.
17.
Anigi S, Romanello MG, Domeneghini C. Ultrastructure of the epithelium lines that the ductuli efferentes testis in domestic eguidae, with particular reference to spermatophagy. Acta Anat (Basel). 1994; 149: 174–184.
18.
Shahreari Sh, Khaki A, Ahmadi-Ashtiani HR, Hajiaghaei R, Rezazadeh Sh. Effects of Danae racemosa on testosterone hormone in experimental diabetic rats. J Med Plants. 2010; 9: 114–119.
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