CASE REPORT
Diagnostic problems in tumour of Th10 vertebra in a 10-year-old girl – Case study
 
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1
Student of the II Faculty of Medicine with English Language Division, Student’s Scientific Orthopedic Group, Medical University of Lublin, Poland
 
2
Student of the I Faculty of Medicine with Dentistry Division, Student’s Scientific Orthopedic Group, Medical University of Lublin, Poland
 
3
Paediatric Orthopedic Clinic, Medical University of Lublin, Poland
 
 
Corresponding author
Tomasz Lach   

Student of the II Faculty of Medicine with English Language Division, Students’ Scientific Orthopedic Group, Medical University, Lublin, Poland
 
 
J Pre Clin Clin Res. 2015;9(2):177-179
 
KEYWORDS
ABSTRACT
Introduction:
Despite a wide range of imaging modalities available today, clinically silent osteolytic changes in the skeletal system occurring in children are still a diagnostic challenge.

Case report:
The study presents the case of 10-year-old girl with a tumour in a thoracic vertebra. The patient was admitted to the Paediatric Orthopedics Clinic in the Paediatric Clinical Hospital in Lublin suffering from severe pain in the thoracic and lumbar spine. The pain had started suddenly. Physical examination showed lumbar spine pain and a forced scoliotic position. To reduce the symptoms, spinal traction, analgetics and myorelaxing drugs were used. X-ray and CT of the spine showed congenital unfused S1-S3 vertebrae. An MRI was scheduled for further diagnosis. After treatment, the symptoms disappeared and the the patient was discharged after 6 days. MRI showed an oval, well-demarcated lesion in the vertebra body and left side of the arch of the Th10 vertebra. The patient was admitted to the Clinic one again. CT scan of the thoracic spine showed an osteolytic lesion in Th10 vertebra. In the spine X-ray irregular vertebral body contour in Th10 vertebra, was seen. There were no signs of neoplastic infiltration. Scintigraphy showed increased radioisotope uptake in spinal processes of Th10 and Th11 vertebrae, which confirmed the MRI results. A transpendicular trepanobiopsy of the Th10 vertebrae was performed to provide material for histopathological examination. Then, a transpedicular stabilization of Th9-Th11 vertebrae and posterior sponylodesis with spinal autografts was performed. Histopathological examination showed no malignant cells but did not help to establish a diagnosis.

Conclusions:
In spite of using all the available diagnostic methods it was impossible to determine the type of lesion in the patient’s spine. Genetic tumour marker test can be considered.

 
REFERENCES (12)
1.
Singh DK, Singh N, Pant MC. Aneurysmal bone cyst: An unusual presentation of back pain. Asian J Neurosurg. 2014 Apr; 9(2): 105–7. doi: 10.4103/1793–5482.136727.
 
2.
Greenspan A. Diagnostyka obrazowa w ortopedii dla lekarza praktyka. Medi Page. Warszawa 2007; 432–448 (in Polish).
 
3.
Touboul E, Khelif A, Guérin RA. Primary tumours of the spine. Initial oncologic aspects: epidemiology, anatomo-prognostic and therapeutic classification. Neurochirurgie. 1989; 35(5): 312–6, 351–2.
 
4.
Barlow E, Davies A, Mangham D. Osteoid osteoma and osteoblastoma: novel histological and immunohistochemical observations as evidence for a single entity. J Clin Pathol. 2013 Sep; 66(9): 768–74.
 
5.
Si MJ, Wang CG, Wang CS, Du LJ, Ding XY, Zhang WB, Lu Y, Zu JY. Giant cell tumours of the mobile spine: characteristic imaging features and differential diagnosis. Radiol Med. 2014 Sep; 119(9): 681–93. doi: 10.1007/s11547–013–0352–1. Epub 2014 Feb 15.
 
6.
Karampalis C, Lenthall R, Boszczyk B. Solid variant of aneurysmal bone cyst on the cervical spine of a child: case report, differential diagnosis and treatment rationale. Eur Spine J. 2013 Mar; 22(3): 523–31.
 
7.
Dormans JP, Kearney SP. Expert's comment concerning grand rounds case entitled “solid variant of aneurysmal bone cyst on the cervical spine of a child: case report, differential diagnosis, and treatment rationale" (by Christos Karampalis, Robert Lenthall, and Bronek Boszczyk). Eur Spine J. 2013 Mar;22(3):532. doi: 10.1007/s00586-013-2668-x. Epub 2013 Jan 29.
 
8.
Jankowski R, Szymaś J, Nowak S, Żukiel R, Sokół B. Pierwotne nowotwory kostne kręgosłupa. Neuroskop. 2009; 11: 86–103 (in Polish).
 
9.
Orguc S, Arkun R. Primary tumours of the spine. Semin Musculoskelet Radiol. 2014 Jul; 18(3): 280–99. doi: 10.1055/s-0034–1375570. Epub 2014 Jun 4.
 
10.
Sujit Nilegaonkar, Sameer Sonar, Ashish Ranade, Madhav Khadilkar. TC99m MDP bone scan in evaluation of painful scoliosis. Indian J Nucl Med. 2010 Apr-Jun; 25(2): 67–69.
 
11.
Dekeuwer P, Odent T, Cadilhac C, Journeau P, Langlais J, Padovani JP, Glorion C, Pouliquen JC. Aneurysmal bone cyst of the spine in children: a 9-year follow-up of 7 cases and review of the literature. Rev Chir Orthop Reparatrice Appar Mot. 2003 Apr; 89(2): 97–106.
 
12.
Peng B, Chen J, Pang X, Hei Y. A kind of specific osteolytic destruction of the vertebral bodies. BMJ Case Rep. 2012 Jun 5; 2012. pii: bcr0320126121. doi: 10.1136/bcr-03–2012–6121.
 
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