Skin lesions in the form of eruptive xanthomasas a first manifestation of severe hyperlipidemia complicated by acute pancreatitis in a patient with newly diagnosed type 2 diabetes
More details
Hide details
Department of Internal Medicine; Independent Public Healthcare Centre in Przeworsk, Poland
Specialist Practice IMAMED Lublin, Poland
Department of Internal Medicine, Medical University of Lublin, Poland
Department of Expert Medical Assistance with Emergency Medicine Unit, Medical University of Lublin, Poland
Grzegorz Nowicki   

Department of Expert Medical Assistance with Emergency Medicine Unit, Medical University of Lublin, ul. Staszica 6, 20-081 Lublin, Poland
J Pre Clin Clin Res. 2014;8(2):113–115
The presence oferuptive xanthomasis associated with lipid disorders particularly hypertriglyceridemia. What’s more, intensify hypertriglyceridaemia >10 mmol/l (880mg%) is a major risk factor for acute pancreatitis. This case concerns a 40-year-old man with skinlesions in the form of eruptive xanthomas accompanied by hypertriglyceridaemi complicated by acute pancreatitis, and then diagnosed with type 2 diabetes with glycated hemoglobin 9,7 g/dl. Seeding of skin lesions appeared 2-3 months before hospitalization and was observed in the direction of molluscum contagiosum.
1. Ginter E, Simko V. Global prevalence and future of diabetes mellitus. Adv Exp Med Biol. 2012; 771: 35–41.
2. Diabetologia kliniczna. Zalecenia kliniczne dotyczące postępowania u chorych na cukrzyce. Diabetol Klin. 2013; 2(supl. A) (in Polish).
3. Burgdorf WHC, Plewig G, Wolff HH, Landthaler M. Dermatologia. Zaburzenia metabolizmu lipidów. Lublin, Wydawnictwo Celej, 2010. p.1244–1249 (in Polish).
4. Cameron JL, Crisler C, Margolis S, et al. Acute pancreatitis with hiperlipemia. Surgery. 1971; 70: 53–61.
5. Haffner SM, Lehto S, Rönnemaa T, Pyörälä K, Laakso M. Mortality from coronary heart disease In subjects with type 2 diabetes and in non diabetic subjects with and without prior myocardial infarction. N Eng J Med. 1998; 339(4): 229–234.
6. Isidro ML. Sexual dysfunction in men with type 2 diabetes. Postgrad Med J. 2012, 88(1037): 152–159.
7. Miranda PJ, DeFronzo RA, Califf RM, Guyton JR. Metabolic syndrome: definition, pathophysiology and mechanizm. Am. Heart J. 2005; 149(1): 33–45.
8. Krauss RM. Lipids and lipoproteins In patients with type 2 diabetes. Diabetes Care. 2004; 27(6): 1496–504.