REVIEW PAPER
Mechanisms controlling the gastrointestinal migrating motor complex
 
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Department of Animal Physiology, Faculty of Veterinary Medicine, University of Environmental and Life Sciences, Wrocław, Poland
CORRESPONDING AUTHOR
Krzysztof Romański   

Department of Animal Physiology, Faculty of Veterinary Medicine, University of Environmental and Life Sciences, C. K. Norwida 31, 50-375 Wrocław, Poland.
 
J Pre Clin Clin Res. 2009;3(1):11–19
 
KEYWORDS
ABSTRACT
The mechanisms controlling the migrating motor complex (MMC) are composed, and so far incompletely recognized. The central portion of the autonomic nervous system exerts rather modulatory effects upon the MMC although the strong inhibitory effects were also observed. The role of the enteric nervous system in the initiation and propagation of the MMC is crucial. However, these peripheral mechanisms are coordinated with central influences exerted by the extrinsic nerves. The basic role of the cholinergic system is thus combined with the adrenergic and non-adrenergic non-cholinergic influences. The hormones appear mainly to disrupt and convert the MMC cycle into the feed pattern. Several hormonal factors are also known to affect the MMC especially to induce its phase III.
 
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